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Construction of a classification model for culprit plaques in acute myocardial infarction based on Raman spectroscopy and related clinical prognosis research

Construction of a classification model for culprit plaques in acute myocardial infarction based on Raman spectroscopy and related clinical prognosis research

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089332
Enrollment
Unknown
Registered
2024-09-06
Start date
2024-09-06
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infraction

Interventions

Sponsors

The 2nd Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients aged 18 years or older and younger than 75 years old; (2) Acute chest pain lasting more than 30 minutes but less than 12 hours; (3) ST segment elevation in two or more adjacent leads of the electrocardiogram (ECG) =0.1mV in the limb leads and =0.2mV in the chest leads, or new complete left (or right) bundle branch block; (4) Unable to complete percutaneous coronary intervention within 120 minutes.

Exclusion criteria

Exclusion criteria: (1) History of intracranial hemorrhage or stroke of unknown location, ischemic stroke in the past 6 months; (2) Central nervous system injury, nervous system tumor or arteriovenous malformation; (3) Major trauma, surgery or head injury in the past 2 months; (4) Gastrointestinal bleeding in the past month, bleeding disease of known cause (excluding menstruation); (5) Clear, highly suspected or unable to rule out aortic dissection (1) Non-compressible puncture (such as liver biopsy, lumbar puncture) within 24 hours; (6) Oral anticoagulant treatment; (7) Pregnancy or 1 week postpartum; (8) Refractory hypertension [systolic blood pressure>180mmHg and/or diastolic blood pressure>110mmHg; (9) Suffering from advanced liver disease, infective endocarditis, active peptic ulcer; (10) Prolonged or invasive resuscitation.

Design outcomes

Primary

MeasureTime frame
Fibrous cap integrity degree;Thrombus;

Countries

China

Contacts

Public ContactYan Fang

The 2nd Affiliated Hospital of Harbin Medical University

fangyan5668@163.com+86 138 3611 2917

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026