Development of Predictive Models for Post-Stroke Cognitive Impairment (PSCI) and Characterization of PSCI

Development of Predictive Models for Post-Stroke Cognitive Impairment (PSCI) and Characterization of PSCI - Development of Predictive Models for Post-Stroke Cognitive Impairment (PSCI) and Characterization of PSCI

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400089327

Enrollment

Unknown

Registered

2024-09-05

Start date

2024-09-10

Completion date

Unknown

Last updated

2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-Stroke Cognitive Impairment

Interventions

Post-Stroke Cognitive Impairment Group:An observational study without implementing any interventions, only collecting data on eye movements, EEG, scales, and demographic factors.

Post-Stroke Non-Cognitive Impairment Group:An observational study without implementing any interventions, only collecting data on eye movements, EEG, scales, and demographic factors.

Eligibility

Sex/Gender

All

Age

35 Years to 75 Years

Inclusion criteria

Inclusion criteria: a) Age between 35 and 75 years old; b) Meets the diagnostic criteria for stroke outlined in the "Diagnostic Guidelines for Major Cerebrovascular Diseases in China 2019," with a confirmed diagnosis of first-ever stroke or no previous stroke with residual cognitive impairment; and has an MMSE score of =10 and an NIHSS language subscale score =2. c) Able to understand the test content and independently cooperate with all testing procedures. d) Patient or their family members provide informed consent for the examination and treatment procedures of this study. e) Completeness and availability of required multimodal data. Note: After enrollment, patients will be grouped based on the MoCA score: MoCA < 26 indicates cognitive impairment, while MoCA = 26 indicates normal cognition.

Exclusion criteria

Exclusion criteria: a) Patients with altered consciousness or those who do not cooperate for other reasons. b) Exclude patients who cannot cooperate with EEG and eye movement examinations, such as those with tremors or seizures. c) Exclude patients with severe cerebrovascular disease, dementia with Lewy bodies, frontotemporal dementia, primary progressive semantic dementia, or other active neurological disease complications. d) Exclude patients with eye movement disorders or visual impairments due to various causes.

Design outcomes

Primary

Measure	Time frame
neuroelectrophysiology;eye movement;	—

Secondary

Measure	Time frame
clinical scales;	—

Countries

China

Contacts

Public ContactHaitao Lu

Beijing Bo'ai Hospital, China National Rehabilitation Center

13051760807@163.com+86 130 5176 0807

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026