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Construction of a Diagnostic Model for Ovarian Epithelial Carcinoma Based on the Analysis of Volatile Organic Compounds in Exhaled Breath Using Mass Spectrometry

Construction of a Diagnostic Model for Ovarian Epithelial Carcinoma Based on the Analysis of Volatile Organic Compounds in Exhaled Breath Using Mass Spectrometry

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089322
Enrollment
Unknown
Registered
2024-09-05
Start date
2024-07-29
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Epithelial Cancer

Interventions

Index test:Constructing a Support Vector Machine (SVM) model to calculate sensitivity, specificity, positive predictive value, and negative predictive value for evaluating the diagnostic performance o

Sponsors

GYNECOLOGIC OF THE SOUTHWEST HOSPITAL OF AUM
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Patients aged between 18 and 70 years old. (2) Patients with ovarian tumors who are candidates for surgical treatment. (3) No history of cancer within the past five years. (4) Capable of follow-up and with good compliance.

Exclusion criteria

Exclusion criteria: (1) Patients who are pregnant. (2) Active infection, defined by at least two of the following conditions: fever, cough, or sputum symptoms; procalcitonin levels greater than 0.05 ng/mL, white blood cell count greater than 9500/µL or less than 3500/µL (converted to ×10^9 per liter by multiplying by 0.001), C-reactive protein levels greater than or equal to 0.5 mg/dL (converted to milligrams per liter by multiplying by 10.0), or absolute neutrophil count greater than 6300/µL or less than 1800/µL. (3) Current sufferers of chronic diseases such as kidney disease, liver disease, diabetes, and other metabolic disorders. (4) Patients who have received treatment for respiratory diseases within the past six months. (5) Patients with insufficient exhaled volume (less than 600 mL).

Design outcomes

Primary

MeasureTime frame
Support Vector Machine Model;

Secondary

MeasureTime frame
Sensitivity;Specificity;Positive Predictive Value;Negative Predictive Value;

Countries

China

Contacts

Public ContactWang Yanzhou

THE SOUTHWEST HOSPITAL OF AUM

1228332744@qq.com+86 186 8089 3816

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026