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Effect of remimazolam toluene sulfonate on intraoperative hemodynamic changes and postoperative recovery in elderly patients undergoing endoscopic retrograde cholangiopancreatography

Effect of remimazolam toluene sulfonate on intraoperative hemodynamic changes and postoperative recovery in elderly patients undergoing endoscopic retrograde cholangiopancreatography

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089307
Enrollment
Unknown
Registered
2024-09-05
Start date
2023-12-21
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary and pancreatic diseases

Interventions

R1 group:Dose of remazolam is 0.15mg/mg
R2 group:Dose of remazolam is 0.2mg/mg
P group:The propofol dose is 2mg/kg

Sponsors

the Second Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective transendoscopic retrograde cholangiopancreatography under general anesthesia; 2.Voluntary participation in the trial and signing of informed consent; 3.Age = 60 years.

Exclusion criteria

Exclusion criteria: 1.A clear history of neurologic or psychiatric disease prior to surgery; 2. A history of alcoholism or drug dependence; 3. History of allergy to the drugs used in this study; 4.Patients with long-term application of narcotic analgesics, sedatives or non-steroidal anti-inflammatory drugs; 5. Patients with severe preoperative combined hepatic and renal dysfunction; 6. Participation in other drug trials within three months or inability to communicate well with the investigator.

Design outcomes

Primary

MeasureTime frame
blood pressure; heart rate;

Secondary

MeasureTime frame
EEG bispectral index;Patient recovery time;Postoperative recovery quality of patients;

Countries

China

Contacts

Public ContactZhou Feng

The Second Hospital of Dalian Medical University

zhou6dl@163.com+86 139 4263 8716

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026