helicobacter pylori
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects must meet all of the following criteria: (1) Adult patients aged 18-70 years; (2) H. pylori infected individuals diagnosed by urea breath test (UBT) or rapid urease test (RUT); (3) have not received standardized H. pylori eradication therapy before; (4) Voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: Individuals who meet any of the following criteria are not eligible to participate in this study: (1) Those who have used antibiotics, bismuth preparations, probiotics, potassium-competitive acid blockers, PPIs, or H2 receptor antagonists in the past 4 weeks or potassium-competitive acid blockers, PPIs, or H2 receptor antagonists in the past 2 weeks. (2) Individuals who are allergic to the study medication. (3) Those who are concurrently using non-steroidal anti-inflammatory drugs, systemic corticosteroids, anticoagulants, or alcohol during treatment. (4) Individuals with severe heart, lung, liver, kidney, or other diseases, or compromised immune systems. (5) Those with acute upper gastrointestinal bleeding, gastrointestinal malignancies, Zollinger-Ellison syndrome, or a history of gastric cancer surgery. (6) Individuals who are pregnant or breastfeeding. (7) Those with mental illness or cognitive impairments that prevent them from cooperating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events;Compliance; | — |
Countries
China
Contacts
Affiliated Hospital of Yangzhou University