Autism Spectrum Disorder
Conditions
Interventions
Before WMT:None
After WMT:None
021 Donor group:None
ABC Effective group of 021 donor group:None
ABC ineffective group of 021 donor group:None
CARS effective group of 021 donor group:None
CARS ineffective group of 021 donor group:None
SDSC effective group of 021 donor group:None
SDSC ineffective group of 021 donor group:None
027 donor group:None
ABC effective group of 027 donor group:None
ABC ineffective group of 027 donor group:None
CARS effective group of 027 donor group:None
CARS ineffective group of 027 donor group:None
SDSC effective group of 027 donor group:None
SDSC ineffective group of 027 donor group:None
6-GIS effective group of 027 donor group:None
6-GIS ineffective group of 027 donor group:None
Sponsors
Department of gastroenterology, the First Affiliated Hospital of Guangdong Pharmaceutical University
Eligibility
Sex/Gender
All
Age
4 Years to 18 Years
Inclusion criteria
Inclusion criteria: In this study, retrospective data will be collected on the children with ASD from the same donor from July 1,2019 to May 31,2024 and the corresponding donor. Inclusion criteria: (1) Children with ASD met the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (a persistent deficiencies in social communication and social interaction; b narrow interests, repetition, and sensory abnormalities; c symptoms must appear in early childhood; d related symptoms caused significant functional impairment in social, occupational or other important areas; e related symptoms could not be explained by mental disability or overall retardation).(2) From July 1,2019 to May 31,2024, two or more courses of WMT were conducted in our hospital, and the fresh bacterial solution of the first course of WMT came from the same donor. (3) The age of the children is greater than or equal to 4 years and less than 18 years. (4) Children and their families can cooperate with the complete collection of medical records.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) Patients received antibiotics within 1 month before WMT: (2) Diagnosed with schizophrenia, childhood depression, (3) Diagnosed with severe organic brain disease or other severe heart, lung, liver or kidney disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Childhood Autism Rating Scale;Autism Behavior Checklist;Sleep Disturbance Scale for Children;6 GI severity indices;The results of intestinal flora sequencing ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine; | — |
Countries
China
Contacts
Public ContactLihao Wu
The First Affiliated Hospital of Guangdong Pharmaceutical University
Outcome results
None listed