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Comparison of liposome bupivacaine and cocktail analgesic regimens for postoperative analgesia in adolescent idiopathic scoliosis: a prospective, double-blind, randomized controlled clinical study

Comparison of liposome bupivacaine and cocktail analgesic regimens for postoperative analgesia in adolescent idiopathic scoliosis: a prospective, double-blind, randomized controlled clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089287
Enrollment
Unknown
Registered
2024-09-05
Start date
2024-09-10
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent idiopathic scoliosis

Interventions

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1.The patient was diagnosed with adolescent idiopathic scoliosis deformity and required posterior spinal fusion; 2. Patients were =12 and =18 years old; 3. The patient does not have any congenital diseases and other underlying conditions that can bring about chronic pain; 4. Patients and their guardians agreed to participate in the study and signed the relevant informed consent form;

Exclusion criteria

Exclusion criteria: 1. The patient has congenital scoliosis deformity or other causes of scoliosis deformity; 2. The patient undergoes secondary revision surgery; 3. The patient has a severe scoliosis deformity with a primary curvature Cobb angle >100°; 4. The patient underwent an anterior and posterior fusion surgery; 5. The patient received Halo-vest frame traction and underwent posterior fusion surgery; 6. Patients were younger than 12 or older than 18 years of age; 7. Patients and their guardians refused to participate in this study;

Design outcomes

Primary

MeasureTime frame
Postoperative dosage of remedial morphine hydrochloride;Time to first postoperative remedial analgesia;VAS pain score;Total drug usage of self-controlled analgesic devices in postoperative;

Secondary

MeasureTime frame
Daily walking distance;Postoperative drain and urinary catheter removal time;The duration of hospital stay;Incidence of postoperative complications;

Countries

China

Contacts

Public ContactLei Wang

West China Hospital, Sichuan University

wanglei_cd@126.com+86 189 8060 6658

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026