Cervical cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Female, aged 30-65 years; 2. Sexual life history; 3. No sexual activity, vaginal medication or irrigation within 72 hours of sampling; 4. Complete clinical data, after pathology or colposcopy clinical diagnosis of cervical precancerous lesions (CIN-II-III grade) and cervical cancer patients (4 stages).
Exclusion criteria
Exclusion criteria: 1. History of HPV vaccination; 2. During pregnancy or within 8 weeks postpartum; 3. Present or past with other systemic malignancies; 4. Previous history of reproductive system surgery or chemoradiotherapy; 5. Used antibiotics, hormones and vaginal microecological improvement preparations in the past 1 month; Have been treated for a variety of reproductive tract infections (such as BV, HPV or its STI) in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Methylated gene;Fusion gene;Vaginal microbiota; | — |
Countries
China
Contacts
Huazhong University of Science and Technology Union Shenzhen Hospital (Nanshan Hospital)