Postoperative delirium
Conditions
Interventions
Postoperative delirium group and non-operative delirium group(Sample size per group depends on postoperative follow-up):None
Sponsors
The First Hospital of Lanzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients aged =18 years with an American Society of Anaesthesiologists physical status (ASA) of I-IV who were scheduled to undergo abdominopelvic surgery under general anaesthesia (including gastric and intestinal tumour resections, hepatic resections, pancreatico-choledochotomy tumour resections, extensive hysterectomies, etc.). Participants were native Chinese speakers and were physically able to take the cognitive tests.
Exclusion criteria
Exclusion criteria: Patients with hepatic encephalopathy, patients who have undergone surgery in the past 12 months, patients with a history of intracranial or cerebrovascular disease, patients with carotid artery disease, patients with psychiatric disorders and on long-term psychotropic medication, patients who are aphasic at the time of the delirium assessment, or who die prior to the delirium assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cerebral oximetry index ;Postoperative delirium;Human serum S100ß protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| electroencephalogram;MoCA score;FRAIL score;Anaesthesia, drug dose, oxygen saturation, heart rate, MAP, end-expiratory CO2 partial pressure, intraoperative rScO2, operative time;Age, gender, BMI, education, hypertension, diabetes mellitus, myocardial infarction, atrial fibrillation, chronic heart failure, history of smoking, current smoker, history of alcohol consumption, COPD, peripheral vascular disease;OptMAP,LLA,ULA; | — |
Countries
China
Contacts
Public ContactLiu Yatao
The First Hospital of Lanzhou University
Outcome results
None listed