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Comparison of liposome bupivacaine and cocktail analgesic regimens for postoperative analgesia in Transforaminal lumbar interbody fusion: a prospective, double-blind, randomized controlled clinical study

Comparison of liposome bupivacaine and cocktail analgesic regimens for postoperative analgesia in Transforaminal lumbar interbody fusion: a prospective, double-blind, randomized controlled clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089275
Enrollment
Unknown
Registered
2024-09-05
Start date
2024-09-10
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative diseases of the lumbar spine

Interventions

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients requiring lumbar TLIF surgery for giant disc herniation, recurrent disc herniation, intervertebral pseudoarthrosis, symptomatic lumbar spondylolisthesis, etc; 2. Patients were =18 and =80 years old; 3. The patient does not have any congenital diseases and other underlying conditions that can bring about chronic pain; 4. Patients agreed to participate in the study and signed the relevant informed consent form;

Exclusion criteria

Exclusion criteria: 1. Patients who are unsuitable for lumbar TLIF surgery because of extensive epidural scarring, arachnoiditis, active infection, nerve root degeneration, or severe osteoporosis; 2. The patient undergoes secondary revision surgery; 3. The patient is less than 18 years old or more than 80 years old; 4. Patients with severe cardiovascular, cerebrovascular and other underlying diseases that are not suitable for surgery; 5. patients and their families refused to participate in this study;

Design outcomes

Primary

MeasureTime frame
Postoperative dosage of remedial morphine hydrochloride;Time to first postoperative remedial analgesia;VAS pain score;Total drug usage of self-controlled analgesic devices in postoperative;

Secondary

MeasureTime frame
Daily walking distance;Postoperative drain and urinary catheter removal time;The duration of hospital stay;Incidence of postoperative complications;

Countries

China

Contacts

Public ContactLei Wang

West China Hospital, Sichuan University

wanglei_cd@126.com+86 189 8060 6658

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 17, 2026