urothelial carcinoma
Conditions
Interventions
Gold Standard:Comprehensive evaluation based on the pathological gold standard, imaging, and other clinical examinations.
Index test:Urine exosome miRNA content
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Suspected bladder cancer patients with gross or microscopic hematuria, aged =18 years; 2) Each clinical trial subject's clinical sample should be fresh and sufficient to allow for both the evaluation of the test reagent and urinalysis. 3) All samples must be sourced from outpatient or inpatient specimens in clinical hospitals, and must have a clinical or pathological diagnosis. 4) All samples should be accompanied by corresponding clinical basic information, including: sample ID (outpatient number, medical record number, contact phone number, and inpatient number), gender, age, smoking history, history of chemical exposure, family history of bladder cancer, and clinical diagnosis information. 5) Control cases with other non-bladder cancer urinary system diseases (ultimately clinically diagnosed as not bladder cancer), including benign prostatic hyperplasia, urinary stones, urinary tract infections, kidney cancer, and others. 6) Healthy subjects undergoing physical examination, aged =18 years, with no history of infectious diseases, mental illnesses, or other major diseases, and currently in good health. Female subjects must not be pregnant or breastfeeding at the time of the physical examination.
Exclusion criteria
Exclusion criteria: 1) Samples missing information such as sample ID (outpatient number, medical record number, or inpatient number), gender, age, clinical diagnosis, etc. 2) Samples that are not fresh. 3) Samples with insufficient volume to complete all required tests. 4) Samples that do not meet the basic criteria for the test reagent or comparison method.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine exosome microRNA;Accuracy;Sensitivity ;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive predicative value; | — |
Countries
China
Contacts
Public ContactGong Yanqing
Peking University First Hospital
Outcome results
None listed