Spinal Cord Compression Caused by Spinal Metastases
Conditions
Interventions
Case series:None
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1)Diagnosed with MSCC due to spinal metastases confirmed by imaging (MRI or CT). (2)Acute or subacute onset of MSCC. (3)Modified Tokuhashi score for spinal metastases = 9, indicating an expected survival time > 6 months. (4)Spinal instability neoplastic score (SINS) = 7, indicating spinal stability. (5)General performance status (Karnofsky score) = 60. (6)No prior radiotherapy or surgical treatment for the spinal metastases before enrollment. (7)Patient refuses or is intolerant to surgery. (8)No other severe comorbidities, such as uncontrolled infections or serious cardiopulmonary diseases, that may affect radiotherapy outcomes or increase treatment risks. (9)No other active malignancies (except for the primary tumor and spinal metastases) to ensure the study's focus. (10)Age 18 years or older. (11)Informed consent obtained from the patient. (12) Accept CT guided spinal cord compression all in one adaptive emergency radiotherapy for spinal metastases.
Exclusion criteria
Exclusion criteria: (1)History of radiotherapy or surgery in the affected spinal region leading to MSCC. (2)Intolerance to radiotherapy. (3)Severe psychiatric or neurological disorders. (4)Pregnant or breastfeeding women. (5)Clear indications that the affected spinal cord region requires decompression surgery first.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local control rate 6 months after radiotherapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological function assessment,;Pain evaluation;Emergency radiotherapy treatment time; | — |
Countries
China
Contacts
Public ContactJunjie Wang
Peking University Third Hospital
Outcome results
None listed