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Impact of oral raceanisodamine Tablets during endometrial preparation in frozen-thawed embryo transfer cycle:a clinical prospective, randomized,double-blinded placebocontrolled trial

Impact of oral raceanisodamine Tablets during endometrial preparation in frozen-thawed embryo transfer cycle:a clinical prospective, randomized,double-blinded placebocontrolled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089254
Enrollment
Unknown
Registered
2024-09-04
Start date
2024-09-05
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility

Interventions

Raceanisodamine group:Since down regulation,raceanisodamine tablets (Hangzhou Minsheng Pharmaceutical Co., Ltd., Chinese medicine approved by H33021706,5mg / tablet) were used 5mg, orally, twice a day
control group:Since down regulation,Vitamin c tablets (Huazhong Pharmaceutical Co., Ltd., Chinese medicine approved by H42020614,0.1g / tablet) were used 0.1g, orally, twice a day, continuously to the

Sponsors

Reproductive Medicine Center,Renmin Hospital,Hubei University of Medicine,Shiyan,People's Republic of China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 38 Years

Inclusion criteria

Inclusion criteria: ? Embryos were obtained using standard IVF-ET or intracytoplasmic sperm injection; ?During the first freeze-thaw embryo transfer cycle of patients, the endometrial preparation protocol adopted the standardized GnRH-a down regulation plus hormone replacement technology of our center; ? only used whole embryo frozen blastocysts; ? patients aged <38 years; ? voluntarily participated in the clinical trial, and was able to conduct the trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: ? Contraindication of raceanisodamine tablets: increased intracranial pressure, acute cerebral hemorrhage, glaucoma, pyloric obstruction, urinary storage, hemorrhagic disease, intestinal obstruction, reflux esophagitis, severe ulcerative colitis, severe heart failure and arrhythmia; ? Intrauterine adhesion; ?Uterine adenomyosis.

Design outcomes

Primary

MeasureTime frame
Embryo implantation rate;

Secondary

MeasureTime frame
Clinical pregnancy rate;

Countries

China

Contacts

Public ContactShengfang Jiang

Reproductive Medicine Center,Renmin Hospital,Hubei University of Medicine,Shiyan,People's Republic of China

3036612325@qq.com+86 137 9782 3546

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026