otitis media
Conditions
Interventions
intervention group:Rivaroxaban 10mg qd orally was administered 6-10 hours after surgery and discontinued on the 7th day after surgery
control group:No anticoagulation treatment
Sponsors
Beijing Tsinghua Changgung Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Middle ear surgery under general anesthesia for patients with ear diseases =40 years old and =80 years old; Operation duration =2 hours.
Exclusion criteria
Exclusion criteria: 1) Patients with venous thrombosis and elevated D-Dimer found by preoperative examination after admission; 2) Patients undergoing anticoagulation or antiplatelet therapy at admission; 3) Risk assessment table for anticoagulant bleeding (HAS-BLED=3); 4) Patients known to be allergic to rivaroxaban; 5) Acute or chronic kidney disease (glomerular filtration rate less than 30ml/min); 6) Life expectancy is not more than 6 months or it is expected to be difficult to complete the interview
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of lower extremity venous thrombosis or pulmonary embolism 1 week after surgery; | — |
Countries
China
Contacts
Public ContactYi Haijin
Beijing Tsinghua Changgung Hospital
Outcome results
None listed