Effects of esketamine on intracranial pressure and emergence agitation during pneumoperitoneum and Trendelenburg position in children

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400089217

Enrollment

Unknown

Registered

2024-09-04

Start date

2024-09-10

Completion date

Unknown

Last updated

2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergence agitation

Interventions

esketamine group:0.5mg/kg esketamine was given during induction

control group:Same dose of saline

Eligibility

Sex/Gender

All

Age

2 Years to 14 Years

Inclusion criteria

Inclusion criteria: Age: Pediatric patients aged 2-14 years. - Gender: unlimited. - Weight: Standard weight for children. - Health status: American Society of Anesthesiologists (ASA) Level I.

Exclusion criteria

Exclusion criteria: Lung disease, history of preterm birth, difficult intubation, neuromuscular disease, or other conditions that may affect intracranial pressure.

Design outcomes

Primary

Measure	Time frame
Optic nerve sheath diameter;	—

Secondary

Measure	Time frame
Intracranial pressure (ICP);Vital signs such as heart rate, blood pressure, respiratory rate, and blood oxygen saturation;Behavioral scoring during anesthesia induction and awakening;Postoperative agitation score during the recovery period;	—

Countries

China

Contacts

Public ContactZhigang Wang

Handan Central Hospital

wzg2737@163.com+86 151 7604 6662

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026