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Exploration of DNA methylation biomarkers for early detection in cervical cancer screening in Dongying City of Shandong Province

Exploration of DNA methylation biomarkers for cervical cancer screening in Dongying City of Shandong Province

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089213
Enrollment
Unknown
Registered
2024-09-04
Start date
2024-09-15
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine Cervical Lesions

Interventions

Training group:None
Validation group:None

Sponsors

Dongying People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Females aged 35-64 years with a history of sexual life; 2. An adequate sample of cervical exfoliated cells for testing can be collected; 3. Sign the informed consent form, be willing and able to accept colposcopy, and have histological results that meet the diagnostic criteria, if needed; 4. No history of cervical cancer and precancerous lesions treatment.

Exclusion criteria

Exclusion criteria: 1. Pregnant women; 2. Women with immunodeficiency; 3. Women with a history of other gynecological malignancies and tumors; 4. Women with incomplete personal information: sample collection unit, name, age, cytology test results, HPV test results, colposcopy pathology results.

Design outcomes

Primary

MeasureTime frame
Sensitivity;Specificity;Positive and negative predictive values;

Secondary

MeasureTime frame
Vaginoscopy referral rate;CIN2 detection rate;

Countries

China

Contacts

Public ContactMin Hao

Dongying People's Hospital

haomin166@126.com+86 186 5468 3456

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026