glaucoma
Conditions
Interventions
the study group:Tang’s Pars Plana Filtering
the control group:Trabeculectomy
Sponsors
Eye Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: All kinds of "refractory glaucoma" with poor prognosis of routine filtering anti-glaucoma surgery combined with maximum tolerated amount of anti-glaucoma drugs still can not control intraocular pressure in normal range and failure of routine filtering anti-glaucoma surgery Including but not limited to: 1. neovascular glaucoma (proliferative diabetic retinopathy retinal vein occlusion ocular ischemia syndrome); 2.Patients with progressive decline in corneal endothelial cell number or high risk of decompensation due to various reasons Including: patients who have undergone multiple intraocular surgery, patients with glaucoma after penetrating keratoplasty, iridocorneal endothelial syndrome (ICE), secondary glaucoma, Axenfeld-Rieger syndrome, corneal endothelial dystrophy related diseases (including Fuchs corneal endothelial dystrophy, posterior pleomorphic corneal dystrophy, congenital hereditary corneal endothelial dystrophy, etc.) 3.Patients with primary or secondary acute angle-closure glaucoma with high intraocular pressure (= 2 weeks) Preoperative evaluation of patients with severe decline in visual function. Patients with corneal edema and corneal endothelial decompensation after anterior segment surgery have high risk of malignant glaucoma 4.true microphthalmia 5.glaucoma after aphakia or intraocular lens implantation 6.Glaucoma secondary to 6 uveitis 7.traumatic glaucoma 8.Malignant glaucoma 9.All kinds of glaucoma mentioned above who failed external drainage surgery
Exclusion criteria
Exclusion criteria: 1.Primary open-angle glaucoma and angle-closure glaucoma with definite prognosis after routine anti-glaucoma surgery 2.congenital glaucoma 3.pigmented glaucoma without surgical treatment 4.There is a potential risk of retinal detachment due to vitreous organization 5.water eye or silicone oil eye after vitrectomy 6.patients with obvious vitreous liquefaction due to high myopia and other reasons 7.absolute glaucoma 8.Those who refuse to sign informed consent 9.can't comply with the follow-up requirements of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure;visual acuity;Visual field;Complications;The number of anti-glaucoma drugs after needle revision;Morphology of filtering bleb; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fundus Photograph;Ophthalmic B-ultrasound; | — |
Countries
China
Contacts
Public ContactXiaobin Xie
Eye Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed