Postoperative chronic pain
Conditions
Interventions
A group:Transcutaneous vagus nerve stimulation + peripheral sternal and saphenous nerve block
B group:Transcutaneous vagus nerve stimulation
C group:Pseudostimulus + peripheral sternal and saphenous nerve block
D group:Pseudostimulus + placebo
Sponsors
The Second Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 89 Years
Inclusion criteria
Inclusion criteria: 1) Age =60 years old; 2) The first elective off-cardiopulmonary bypass surgery; 3) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1) Dementia patients (MMSE<24 points); 2) A history of neuropsychiatric disease, or a history of neuropsychiatric disease; 3) Visual and hearing impairment and difficulty communicating; 4) Ear point skin damage or inflammation, such as ear diseases (such as tympanic membrane perforation, etc.); 5) Drug and alcohol abuse; 6) Have participated in other interventional studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of chronic pain 3 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| score of chronic pain 3 months after surgery;Incidence of perioperative anxiety;Score of perioperative anxiety;Intraoperative EEG analysis;Postoperative time-weighted pain score;Postoperative recovery quality score;Incidence of postoperative adverse events;Postoperative 3-month incidence of neuropathic pain; | — |
Countries
China
Contacts
Public ContactLining Huang
The Second Hospital of Hebei Medical University
Outcome results
None listed