Postoperative sleep disorders
Conditions
Interventions
Intraoperative continuous intravenous pumping of dexmedetomidine group:Induction of anesthesia: dexmedetomidine 1µg/kg was pumped intravenously within ten minutes, and the rate was adjusted to 0.4ug/k
a postoperative intravenous analgesia pump was connected at the end of the operation, and the analgesia pump was formulated as sufentanil 0.04µg/kg/h, which is the same as dexmedetomidine 0.04µg/kg/h
Postoperative intravenous analgesic pump with dexmedetomidine group:Induction of anesthesia: saline was pumped in at the same rate as the end of intravenous pumping of dexmedetomidine 1µg/kg for ten m
a postoperative intravenous analgesic pump was connected at the end of the surgery, and the analgesic pump was formulated with sufentanil 0.04µ g/kg/h, dexmedetomidine 0.04 µg/kg/h, flurbiprofenate 0.
Intraoperative continuous pumping + dexmedetomidine added to postoperative intravenous analg
Sponsors
Department of Anesthesiology and Surgery, The First Hospital of Lanzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) patients undergoing elective laparoscopic abdominal surgery at the First Hospital of Lanzhou University; (2) aged 18-65 years; and (3) requiring postoperative PCIA;
Exclusion criteria
Exclusion criteria: (1) history of sleep disorder (use of sleep-promoting medications or Stop-bang score =3 in January preoperatively); (2) long-term preoperative use of opioids, sedatives, antidepressants, or anxiolytics; (3) preoperative history of depression, schizophrenia, epilepsy, or Parkinson's disease; inability to provide informed consent (coma, severe dementia, or speech impairment); sick sinus syndrome, sinus bradycardia (6 h; and (7) failure to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective sleep quality on the first postoperative day; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative stress level;Resting pain level on postoperative day 1;sedation level;delirium;Inflammation level on the first postoperative day; | — |
Countries
China
Contacts
Public ContactLiu Yatao
The First Hospital of Lanzhou University
Outcome results
None listed