Tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Exposure group: patients with gastrointestinal tumors who were assessed by clinicians for the presence of mental stress stimuli. Control group: according to the age and gender factors, corresponding to the exposure group in the ratio of 1:1, matching patients with digestive tract tumors not accompanied by mental stress stimulation. (1) Patients were of any gender and aged between 18 and 80 years; (2) Right-handedness (3) Subjects were conscious, able to understand and cooperate in completing the questionnaire, with clear responses and informed consent to the study; (4) Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Those with mood disorders due to somatic diseases or organic brain diseases; (2) Those with a history of suicide attempts, refractory depression, seizures, bipolar disorder, schizophrenia, or schizoaffective disorder; (3) Those with a positive pregnancy test; (4) Those with malignant tumors of the stomach and those who have undergone surgery for gastrointestinal diseases; (5) Those who have taken non-steroidal anti-inflammatory drugs, proton pump inhibitors, gastric mucosal protectants, and other drugs that may damage/repair the gastric mucosa in the last 6 months; (6) Long history of smoking and alcohol consumption with alcohol intake present on day 1 before enrollment; (7) Those with hepatic, renal, hematologic, pulmonary, cardiovascular, gastrointestinal, musculoskeletal, dermatologic, genitourinary, neurologic, or any other acute or chronic medical condition that limits the subject's ability to complete or participate in this clinical study; (8) Those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tumor pathology; | — |
Secondary
| Measure | Time frame |
|---|---|
| general characteristics;biochemical index;stress rating scale; | — |
Countries
China
Contacts
Zhangjiagang Hospital of Traditional Chinese Medicine