patent foramen ovale associated stroke
Conditions
Interventions
PFO--associated Stroke Group,PFO--AS Group:Patients diagnosed with patent foramen ovale (PFO) and concurrent embolic cerebral ischemic lesions (CS) will be observed and assessed.
Control Group:Patients diagnosed with patent foramen ovale (PFO) without embolic cerebral ischemic lesions (CS) will be observed and assessed.
Sponsors
The Second Affiliated Hospital of Army Medical University(Xinqiao Hospital)
Eligibility
Sex/Gender
All
Age
14 Years to 79 Years
Inclusion criteria
Inclusion criteria: ?cTTE combined with TEE confirms the presence of PFO; ?Head CT/MRI is performed to determine if there are embolic cerebral ischemic lesions; ?Clinical symptoms present as migraine or no obvious symptoms.
Exclusion criteria
Exclusion criteria: ?Assessment of high-risk atherosclerotic plaques in the aorta and cervical arteries by CTA; ?Identification of high-risk cardiac sources of emboli through ECG, 24-hour Holter monitoring, TTE, or TEE, such as atrial fibrillation, coronary artery disease, thrombosis, or valve vegetations; ? Combined with serious heart and lung diseases, unable to cooperate well to complete the examination; ? Poor image quality.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| left atrium antero-posterior diameter;Right Atrial Left-Right Diameter;Early Diastolic Blood Flow Velocity across the Mitral Valve;Early Diastolic Motion Velocity of the Interventricular Septal Side of the Mitral Valve Annulus; | — |
Primary
| Measure | Time frame |
|---|---|
| Grading of Right-to-Left Shunt Volume Associated with Patent Foramen Ovale (PFO) at rest and during Valsalva maneuver;Height of PFO;Length of PFO;Left Atrial Orifice Diameter of PFO during Valsalva Maneuver;Right Atrial Orifice Diameter of PFO during Valsalva Maneuver;Hypermobile interatrial septum;Angle between IVC and PFO;Septum secundum height;Septum secundum thickness;Septum primum thickness;Chiari Network Or Eustachian Valve;Atrial Septal Aneurysm,ASA;Age;Gender;Hegiht;Weight;Hypertension;Diabetes Mellitus;Smoking;History of Deep Vein Thrombosis;History of Pulmonary Embolism;History of Cranial CT or MRI; | — |
Countries
China
Contacts
Public ContactXu yali
Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University)
Outcome results
None listed