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Effect of low-dose norepinephrine perioperative application on prognosis of renal transplantation

Effect of low-dose norepinephrine perioperative application on prognosis of renal transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089155
Enrollment
Unknown
Registered
2024-09-03
Start date
2024-09-10
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal failure

Interventions

The norepinephrine group and the dopamine group:Pump norepinephrine to maintain MAP= basal MAP. If NE=0.2ug/(kg.min) , appropriate dobutamine should be added to avoid decreased organ perfusion due to
The dopamine group:Pump dopamine respectively to maintain MAP= basal MAP. If DA=15ug/(kg.min), appropriate dobutamine should be added to avoid decreased organ perfusion due to strong vasoconstriction

Sponsors

Shenzhen Third People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ASA ? ~ ?, age 18~60 years old, gender not limited, regular dialysis, stable blood pressure control, intended to perform cadaveric kidney transplantation under general anesthesia.

Exclusion criteria

Exclusion criteria: Arrhythmia, basal heart rate 90 beats/min, heart, lung, and liver insufficiency, multiple and combined organ transplants.

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure;Heart rhythm;Creatinine;urine volume;cardiovascular accident;

Secondary

MeasureTime frame
infection;hospital stays;rejection reaction;Dobutamine dosage;

Countries

China

Contacts

Public ContactHan Yakun

Shenzhen Third People's Hospital

yakun361@163.com+86 188 9877 9020

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026