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Study on the effective dose of cyclopofol combined with sufentanil for painless gastrointestinal endoscopy by age and gender factors

Study on the effective dose of cyclopofol combined with sufentanil for painless gastrointestinal endoscopy by age and gender factors

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089147
Enrollment
Unknown
Registered
2024-09-02
Start date
2024-09-02
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless gastrointestinal endoscopy

Interventions

Young male group:The fixed dose of sufentanil was 0.1 µ g/kg, the initial dose of cyclopofol was 0.4 mg/kg, and the dose gradient was 0.05 mg/kg When MOAA/S is less than or equal to 1 min, the dose of
If gastroscope implantation reaction occurs, a dose gradient is up-regulated
Young Female Category:The fixed dose of sufentanil was 0.1 µ g/kg, the initial dose of cyclopofol was 0.4 mg/kg, and the dose gradient was 0.05 mg/kg When MOAA/S is less than or equal to 1 min, the do
Middle-aged male group:The fixed dose of sufentanil was 0.1 µ g/kg, the initial dose of cyclopofol was 0.4 mg/kg, and the dose gradient was 0.05 mg/kg When MOAA/S is less than or equal to 1 min, the d
Middle-aged female group:The fixed dose of suf

Sponsors

Huludao Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) ASA grade I.-II., BMI 18-25 kg/m2, gender is not limited. (2) Meet the indications for painless gastrointestinal endoscopy. (3) Aware of the purpose of this research and have signed a written consent form.

Exclusion criteria

Exclusion criteria: (1) Those who are allergic to or contraindicated to opioids, cyclopofol and their drug components. (2) Patients with a history of severe cardiopulmonary diseases, a history of psychiatric or neurological diseases, and severe muscle weakness. (3) Those who are unable to obtain informed consent.

Design outcomes

Primary

MeasureTime frame
ED50;ED95;

Secondary

MeasureTime frame
Presence or absence of body movement;Blood pressure;heart rate;Oxygen saturation;

Countries

China

Contacts

Public ContactDing Baochun

Huludao Central Hospital, Liaoning Province

dingbc8888@163.com+86 133 7290 6800

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026