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Effects of nalbuphine and meperidine on postoperative uterine contraction pain in patients undergoing artificial abortion or hysteroscopy under general anesthesia

Effects of nalbuphine and meperidine on postoperative uterine contraction pain in patients undergoing artificial abortion or hysteroscopy under general anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089143
Enrollment
Unknown
Registered
2024-09-02
Start date
2024-09-30
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Nalbuphine group:Preoperatively, nalbuphine was administered intravenously at a dose of 0.1 mg/kg
Phloroglucin group:Phloroglucin was administered intravenously preoperatively at doses of 40 mg or 80 mg depending on the patients weight

Sponsors

Affiliated Shunde Hospital of Jinan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients included in the study scheduled for elective general anesthesia for artificial abortion or hysteroscopy, aged 18-45 years, classified as ASA grade I or II, with a BMI ranging from 18 kg/m² to 30 kg/m², and without preoperative respiratory system diseases with normal airway assessment.

Exclusion criteria

Exclusion criteria: Refusal to participate or unsuitability for the trial includes patients with contraindications to anesthesia surgery, those who have used anesthesia, sedatives, or opioid drugs within 24 hours prior to surgery, patients with severe myasthenia gravis, allergies to relevant drugs, liver or kidney dysfunction combined with endocrine or metabolic diseases, patients with mental or neurological disorders, moderate to severe sleep apnea, and those with unstable vital signs due to various serious illnesses.

Design outcomes

Primary

MeasureTime frame
VAS scores at 30 minutes, 1 hour, and 24 hours after surgery;

Secondary

MeasureTime frame
Changes in vital signs at different time points;Patient comfort and satisfaction postoperatively;recovery time and adverse reactions post-surgery;Physician satisfaction;

Countries

China

Contacts

Public ContactZhang Zhongqi

Affiliated Shunde Hospital of Jinan University

jxzzq11@139.com+86 137 9868 2324

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026