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Establishing a Predictive Model for the Risk of Postoperative Delirium Utilizing a Nested Case-Control Design in Low Central Venous Pressure Liver Resection

Establishing a Predictive Model for the Risk of Postoperative Delirium Utilizing a Nested Case-Control Design in Low Central Venous Pressure Liver Resection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089128
Enrollment
Unknown
Registered
2024-09-02
Start date
2024-09-06
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Postoperative delirium group:None
Postoperative normal group:None

Sponsors

The First Hospital of Lanzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ASA status is I-III; Age= 18 years old; BMI 18-28 kg/m2; Be conscious and have the ability to think independently; Planned low-central venous pressure hepatectomy; Non-acute fragility brain function (cerebral hemorrhage, cerebral infarction, transient ischemic attack (TIA), cerebrovascular stenosis, history of PD, long-term headache and dizziness, no seizures or corresponding clinical symptoms within 3 months); Agree to participate in a clinical study.

Exclusion criteria

Exclusion criteria: Patients with intracranial hypertension (hydrocephalus, brain tumors, cerebral space-occupying lesions, etc.); History of surgery, trauma, injury, and infection of the forehead; Patients with a history of major depression, schizophrenia, and other psychoneurological disorders or who have taken antipsychotic or antidepressant medications; Patients with severe impairment of vision and hearing, unable to communicate properly; Patients with serious underlying diseases other than hypertension, diabetes, COPD, and underlying diseases related to fragile brain function as defined in the inclusion criteria (such as patients with acute coronary syndrome, severe arrhythmia, heart, liver, and renal failure, etc.); Patients with moderate and below preoperative anemia (Hb < 90 g/L); Patients with preoperative arterial partial pressure of oxygen < 70 mmHg; Patients undergoing emergency surgery or switching to open surgery due to unforeseen circumstances; Patients who have already participated in other clinical studies may affect the results of this study.

Design outcomes

Primary

MeasureTime frame
Cerebral oxygen saturation;Systemic inflammation indicator;Postoperative delirium;Hemodynamic indicators;—

Countries

China

Contacts

Public ContactYatao Liu

The First Hospital of Lanzhou University

liuyt@lzu.edu.cn+86 181 5210 7860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026