acute myocardial infarction
Conditions
Interventions
control group :Use of antiplatelet drugs
experimental group 1:Use antiplatelet drugs + morphine
experimental group 2:Use antiplatelet drugs +Oliceridine
Sponsors
Mindong Hospital of Ningde City
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) 18 years old = age < 75 years old; 2) meet the ACS diagnostic criteria of the "2023 ESC Acute Coronary Syndrome (ACS) Management Guidelines"; 3) can fully understand the informed consent form of this trial and voluntarily sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1) Cardiogenic shock; 2) Anyone who has been using antiplatelet drugs for a long time; 3) A history of acute myocardial infarction or unstable angina within 3 months; or a history of revascularization surgery (PCI or CABG); 4) Patients with known severe liver or kidney disease, dialysis treatment, or estimated glomerular filtration rate [eGFR] <30ml/min/1.73m2; 5) Patients with bronchial asthma and cor pulmonale; 6) Patients with other serious diseases that may prevent their enrollment or affect their survival, such as malignant tumors and AIDS; 7) Patients with cognitive impairment or unable to take care of themselves; 8) Pregnant or lactating, or planning pregnancy; 9) After organ transplantation; 10) Participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ticagrelor blood concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Platelet reaction; | — |
Countries
China
Contacts
Public ContactFengming Huang
Mindong Hospital of Ningde City
Outcome results
None listed