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The observation of the efficacy and mechanism study of TENS in alleviating obesity combined with metabolic syndrome patients

The observation of the efficacy and mechanism study of TENS in alleviating obesity combined with metabolic syndrome patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089104
Enrollment
Unknown
Registered
2024-09-02
Start date
2024-09-09
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity with metabolic syndrome

Interventions

Peripheral stimulus group:After skin cleaning, 5×5 cm self-adhesive electrodes were used. One electrode was located on the dorsal side of the first and second metacarpal bones, and the other electrode
Central Stimulation group:After cleansing the skin, 5×5 cm self-adhesive electrodes were applied, with one electrode located next to the T4 vertebra and the other next to the L2 vertebra. Treatment st
False stimulus group:The position of the electrode paste is selected randomly (coin toss), but no current treatment is available.

Sponsors

Kunming Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ?Adults who are obese (body mass index =30 kg/m2 ) and between 18 and 60 years of age; ?Comorbid metabolic syndrome (MetS is diagnosed in patients with three or more of the following five risk factors: a. Waist circumference measurement =97 cm in men and women =88 cm in women; b. Triglyceride level =150 mg/dL or medication; c. High-density lipoprotein level 100 mg/dL or medication); ? Individuals who actively maintain healthy lifestyle habits; ? Willingness to participate in treatment on a regular basis.

Exclusion criteria

Exclusion criteria: ? Obesity is caused by an endocrine disease; ?Suffering from mental illness or other conditions that may alter their response to the treatment of the disease; ?Have a substance abuse problem or use of alcohol, diet pills, or special dietary restrictions; ? Planning to become pregnant or becoming pregnant during the study; ? Having undergone bariatric surgery; ? Refuse to participate in the trial or sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Body Mass Index(BMI);Fasting blood glucose;

Secondary

MeasureTime frame
glycosylated hemoglobin;Triglyceride;blood pressure;insulin;Adiponectin;Catecholamines;Catecholstatin;IL-1ß;IL-6;

Countries

China

Contacts

Public ContactYang Lei

Kunming Second People's Hospital

leon_yang30@163.com+86 150 2515 3703

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026