Sarcopenia
Conditions
Interventions
Sarcopenia group:Propofol (Dixon modified sequential method)
Non-sarcopenia group:Propofol (Dixon modified sequential method)
Sponsors
Nanjing Medical University Affiliated Wuxi People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: a. Paients with certain comprehension and language skills and able to cooperate; b. Ultrasound detection of rectus femoris muscle depth = 1.8cm or = 2.8cm; c. American Society of Anesthesiologists (ASA) classification I-III and = 65 years old.
Exclusion criteria
Exclusion criteria: a. Propofol allergy; b. History of opioid or alcohol abuse, long-term use of sedative-hypnotic drugs, current use of psychotropic drugs, oral glucocorticoids or immunosuppressive drugs; c. Severe liver and kidney insufficiency, severe respiratory diseases, patients with potentially difficult airways, thyroid dysfunction, preoperative neurodegenerative diseases such as AD, dementia and other diseases that cannot be communicated; d. Patients with severe osteoarthritis or neuromuscular diseases resulting in impairment or inconvenience of walking; e. Patients with BIS value less than 80 before induction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;bispectral index;EC50; | — |
Countries
China
Contacts
Public ContactZhang Xin
Wuxi People's Hospital
Outcome results
None listed