Obesity
Conditions
Interventions
Dietary intervention and placebo group :Dietary intervention and Oral placebo
dietary intervention and animal Bifidobacterium lactis subsp. lactis ProSci-246 group:dietary intervention and Oral probiotic animal Bifidobacterium lactis subsp. lactis ProSci-246
Sponsors
Inner Mongolia Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Children and adolescents aged 6-17, regardless of gender 2. Body mass index (BMI) meets the obesity criteria for this age group 3. The guardian shall sign an informed consent form in accordance with regulations and be able to accept the patient's treatment method.
Exclusion criteria
Exclusion criteria: 1. Non alcoholic fatty liver and other digestive system diseases, as well as obesity related symptoms such as insulin resistance 2. Significant dietary adjustments or extreme eating habits in the past 3 months 3. And those who have been taking antibiotics or probiotic preparations for a long time in the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose;lipids four ( CHOL, TG, LDL-C HDL-C);uric acid; gut microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal barrier function indicators (D-lactate, diamine oxidase (DAO), bacterial endotoxin (LPS));hemoglobin; | — |
Countries
China
Contacts
Public ContactMa Cuicui
Inner Mongolia Autonomous Region People's Hospital
Outcome results
None listed