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effect of ultrasound-guided bupivacaine liposome transversus abdominis plane block for laparoscopic colorectal cancer surgery: a randomized controlled study

effect of ultrasound-guided bupivacaine liposome transversus abdominis plane block for laparoscopic colorectal cancer surgery: a randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089080
Enrollment
Unknown
Registered
2024-09-01
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Observation group:Prior to surgery, ultrasound-guided bupivacaine liposome transversus abdominis plane block (bilateral)
control group:Before skin suturing, the surgeon used 20ml of 0.5% ropivacaine to infiltrate and block the skin around the incision site

Sponsors

Beijing Friendship Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: A. Patients planning to undergo laparoscopic assisted radical resection for colorectal cancer; B. Age range from 30 to 75 years old; C.BMI 18~30 kg/m2; D. ASA classification 1-2 levels; E. Understand the informed consent form and agree to sign it before this study.

Exclusion criteria

Exclusion criteria: A. There are contraindications for regional nerve block (puncture site infection, coagulation dysfunction, local anesthetic allergy); B. Combining chronic pulmonary and bronchial diseases, old cerebral infarction, transient ischemic attack, sleep apnea syndrome, liver and kidney dysfunction, or mental illness; C. Long term use of opioid drugs; D. Refusing to sign informed consent forms, etc.

Design outcomes

Primary

MeasureTime frame
Opioid dosage 72 hours after surgery;

Secondary

MeasureTime frame
Intraoperative dosages of remifentanil and propofol;Time of first postoperative analgesia and number of remedies;NRS scores;Incidence of postoperative nausea and vomiting;Length of hospital stay;Patient satisfaction (on a percentage scale, with 100 being very satisfied);First landing time;

Countries

China

Contacts

Public ContactHu zhefna

Beijing Friendship Hospital, Capital Medical University

huzhenfa1008@sina.com+86 159 0154 7614

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026