Dementia
Conditions
Interventions
Active:active tDCS with cognitive training
Sham:Sham tDCS with cognitive training
Sponsors
The University of Hong Kong
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: - 65 years of age or above - Right-handedness Chinese as defined by Edinburgh handedness inventory - Cantonese speaking - Fulfil the criteria of Major neurocognitive disorder, as defined by the 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) - Clinical Dementia Rating Global score = 1
Exclusion criteria
Exclusion criteria: - Active diagnosis of mood disorder or psychosis - Alcohol or substance dependence - Initiation or change in dose of cognitive enhancer within 6 months prior to the onset of the study - Poor physical condition and mobility - Having regular cognitive training (as defined by at least three 1-hour weekly structured and standardized cognitive training in recent 3 months - Receiving tDCS within 2 months prior to the onset of study - Significant communication or visual impairment - Having metal implant in area above upper back, or having metal crown or metal brace, or pacemaker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| N-back task performance in terms of reaction time and % of correct;Forward and Backward digit span; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical dementia rating – sum of boxes;Chinese version of the neuropsychiatric inventory (CNPI);Trail making test; | — |
Countries
China
Contacts
Public ContactCheng Pak Wing
The University of Hong Kong
Outcome results
None listed