colorectal neoplasia
Conditions
Interventions
The oxycodone group:Postoperative administration of oxycodone PCIA pump(1mg/ml)
The Sufentanil group:Postoperative administration of sufentanil PCIA pump(1ug
/ml)
Sponsors
Huazhong University of Science and Technology Union Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 18 years = age =60 years; Not limited to men and women, nationality; General anesthesia surgery, the expected operation time is more than 2 hours, and the operation end time is before 12:00pm; Solicit comments from patients or their families and agree to participate in this trial.
Exclusion criteria
Exclusion criteria: He was admitted to ICU directly after surgery. Pregnancy or lactation; Had a solid organ or bone marrow transplant; Diseases that may affect immune-related indicators, such as autoimmune diseases such as rheumatoid arthritis and SLE or malignant hematological tumors (leukemias and lymphomas, etc.); Acute brain injury (traumatic brain injury, subarachnoid hemorrhage, acute ischemic stroke, acute intracranial hemorrhage, acute intracranial infection); Chronic kidney disease; Acute myocardial infarction or severe heart failure (NYHA: Level 4); Severe chronic liver disease (Child-Pugh: Grade C); Deafness, aphasia, mental illness or severe cognitive impairment; Tracheal catheter was removed within 24 hours after operation. Unwillingness or unwillingness to provide informed consent or poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines and lymphocyte subsets; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS scores;Subjective sleep rating; | — |
Countries
China
Contacts
Public ContactChunmei Lin
Huazhong University of Science and Technology Union Shenzhen Hospital
Outcome results
None listed