hypoxemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a. Aged 65-80 years; b. Patients scheduled for gastroscopy and those undergoing gastroscopic polypectomy/clamping and gastric mucosal biopsy; c. ASA classification I-III; d. Signed informed consent
Exclusion criteria
Exclusion criteria: a. Severe cardiovascular disease, including a history of myocardial infarction and unstable angina within the past 6 months, severe arrhythmias, severe heart failure, aortic aneurysm, and patients in shock; b. History of acute pharyngitis and tonsillitis, cervicofacial trauma, burns and deformities; c. History of partial food drug allergy, such as propofol, egg, soy or albumin allergy; d. baseline pulse oximetry < 95 %, severe respiratory disease including severe pneumonia or other infectious fevers, asthmatic dyspnea, and severe pulmonary dysfunction; e. established or suspected abuse or chronic application of narcotic analgesics; f. Mental disorders that make it difficult to cooperate; g. Pregnant, lactating women; h. Abnormal coagulation; i. Esophageal stenosis or cardia obstruction. j. Participation in other studies within 30 days;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia (75% < SpO2 < 90% and 5s < duration < 60s); | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hypoxemia;Recovery time from hypoxemia and subclinical respiratory depression;Airway interventions;operating time;Total dose of propofol;Number of gastroscopy intubations;Postoperative satisfaction scores for anesthesiologists, and endoscopists; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Sun Yat-sen University