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Evaluation of the efficacy and safety of bi-level positive airway pressure applied to the prevention and treatment of hypoxemia during painless gastroscopy in the elderly--a prospective, multicenter, randomized controlled study

Evaluation of the efficacy and safety of bi-level positive airway pressure applied to the prevention and treatment of hypoxemia during painless gastroscopy in the elderly--a prospective, multicenter, randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089031
Enrollment
Unknown
Registered
2024-08-30
Start date
2024-06-30
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoxemia

Interventions

nasal cannula for oxygen:nasal cannula for oxygen

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: a. Aged 65-80 years; b. Patients scheduled for gastroscopy and those undergoing gastroscopic polypectomy/clamping and gastric mucosal biopsy; c. ASA classification I-III; d. Signed informed consent

Exclusion criteria

Exclusion criteria: a. Severe cardiovascular disease, including a history of myocardial infarction and unstable angina within the past 6 months, severe arrhythmias, severe heart failure, aortic aneurysm, and patients in shock; b. History of acute pharyngitis and tonsillitis, cervicofacial trauma, burns and deformities; c. History of partial food drug allergy, such as propofol, egg, soy or albumin allergy; d. baseline pulse oximetry < 95 %, severe respiratory disease including severe pneumonia or other infectious fevers, asthmatic dyspnea, and severe pulmonary dysfunction; e. established or suspected abuse or chronic application of narcotic analgesics; f. Mental disorders that make it difficult to cooperate; g. Pregnant, lactating women; h. Abnormal coagulation; i. Esophageal stenosis or cardia obstruction. j. Participation in other studies within 30 days;

Design outcomes

Primary

MeasureTime frame
Incidence of hypoxemia (75% < SpO2 < 90% and 5s < duration < 60s);

Secondary

MeasureTime frame
Duration of hypoxemia;Recovery time from hypoxemia and subclinical respiratory depression;Airway interventions;operating time;Total dose of propofol;Number of gastroscopy intubations;Postoperative satisfaction scores for anesthesiologists, and endoscopists;

Countries

China

Contacts

Public ContactLuo Gangjian

The Third Affiliated Hospital of Sun Yat-sen University

luogj@mail.sysu.edu.cn+86 189 2210 2871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026