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Effect of different administration modes of dexamethasone combined with erectile muscle and anterior serration muscle plane block on analgesia after video-assisted thoracoscopic surgery: a prospective, randomized controlled tria

Effect of different administration modes of dexamethasone combined with erectile muscle and anterior serration muscle plane block on analgesia after video-assisted thoracoscopic surgery: a prospective, randomized controlled tria

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089026
Enrollment
Unknown
Registered
2024-08-30
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

ropivacaine 0.375% group:30min before operation, Ultrasound?guided erector spinae block combined with serratus anterior plane block was given with 40 ml of 0.375% Ropivacaine ,20ml each.2ml of normal
ropivacaine 0.375% and perineural dexamethasone 10 mg group:30min before operation, Ultrasound?guided erector spinae block combined with serratus anterior plane block was given with 40 ml of 0.375% Ro
ropivacaine 0.375% with i.v. dexamethasone 10 mg group:30min before operation, Ultrasound?guided erector spinae block combined with serratus anterior plane block was given with 40 ml of 0.375% Ropivac

Sponsors

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years old; 2. ASA?~? 3. elective video-assisted thoracoscopic surgery (lobectomy, lung segmentectomy, lung wedge resection).

Exclusion criteria

Exclusion criteria: ? Contraindications to regional nerve blocks, including infection at the injection site or bleeding disorders ; ? Patients allergy to any of the drugs used in this trial; ?Patients with severe cardiovascular, cerebrovascular, respiratory diseases and abnormal liver and kidney function before surgery; ?Patients with preoperative chronic pain and a history of opioids,hormones or non-steroidal drugs therapy ? History of previous type 1 or type 2 diabetes mellitus; ?BMI=30kg/?; ?Failure to communicate normally: hearing impairment, language comprehension impairment, mental illness, etc.; (8) has been participated in other investigators.

Design outcomes

Primary

MeasureTime frame
Effective analgesic duration;

Secondary

MeasureTime frame
numerical rating scale ; effective press times of Patient-controlled Intravenous Analgesia;Opioid Consumption;Time to first remedial analgesia ;number of remedial analgesia;Intraoperative blood pressure;Intraoperative heart rate ;Intraoperative pulse oxygen saturation;Ramsay;Pittsburgh sleep quality index;Patient satisfaction score;15-item Quality of Recovery;Time of first getting out of bed ;Time of first eating;duration of chest tube drainage; length of hospital stay;

Countries

China

Contacts

Public ContactZhao LInlin

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical Universi

lin1675@163.com+86 181 6877 7313

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026