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Evaluation of the effectiveness of a novel arc-shaped multichannel rectal intracavitary applicator based on pelvic MRI images for the treatment of rectal cancer

Evaluation of the effectiveness of a novel arc-shaped multichannel rectal intracavitary applicator based on pelvic MRI images for the treatment of rectal cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089009
Enrollment
Unknown
Registered
2024-08-30
Start date
2024-08-31
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Locally advanced rectal cancer or locally recurrent (without distant metastasis) rectal cancer

Interventions

rectal cancer group :afterloading brachytherapy with the novel arc-shaped multi-channel rectal intracavitary applicator

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age > 18 years(based on the date of signing the informed consent form) 2. Patients with locally advanced rectal cancer or locally recurrent (without distant metastasis) rectal cancer who are suitable for afterloading brachytherapy treatment. 3. Patients who are able to be treated with rear-loading radiotherapy as determined by the investigator based on his/her medical history, physical examination, and vital signs 4. Agree to participate in this study and follow the requirements of this study

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiopulmonary insufficiency or other vital organ insufficiency. 2. Patients with severe bleeding tendency or coagulation disorders. 3. Patients with rectal perforation or other serious complications. 4. Patients judged by the investigator to be unsuitable to participate in this clinical study.

Design outcomes

Primary

MeasureTime frame
Incidence of adverse reactions;

Secondary

MeasureTime frame
ORR;PFS;OS;LRFS;HRQoL;

Countries

China

Contacts

Public ContactWang Hao

Peking University Third Hospital

hhbysy@126.com+86 186 1120 7267

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026