Patients with lung surgery
Conditions
Interventions
group A:Laryngeal anesthetic tube is given 10ml of normal saline for the airway path of the double lumen tube
group B:Laryngeal anesthetic tube is given to the double-lumen tube airway path 2% lidocaine 10 ml
group C:Laryngeal anesthetic tube is given to the double-lumen tube airway pathway alkalinized lidocaine (2% lidocaine 9ml + 5% sodium bicarbonate solution 1ml) 10ml
Sponsors
Anhui Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age 18~75 years old; 2) ASA: I~III level; 3) Patients undergoing thoracic surgery who are going to undergo double-lumen bronchial intubation; 4) Agree to participate in the clinical study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) predict difficult airway. 2) allergy to topical anesthesia or other anesthetics. 3) severe arrhythmias, such as HR=50 bpm at rest, conduction block (double bundle branch block, second- or third-degree block), frequent premature ventricular contractions, QTc: =450 ms for males, =470 ms for females. 4) poorly controlled hypertension (sitting systolic blood pressure (SBP) = 160 mmHg and/or sitting diastolic blood pressure (DBP) =100 mmHg) taking antihypertensive drugs). 5) Severe heart and brain organic lesions, severe liver and kidney dysfunction and endocrine diseases. 6) Patients with psychiatric illness, long-term use of psychotropic drugs, or cognitive dysfunction judged to be lacking the ability to give informed consent. 7) Pregnant or lactating patients. 8) Other patients who are considered by the investigators to be unsuitable to participate in this program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of reactive tachycardia (>120bpm).;Incidence of reactive hypertension (> basal value 130%); | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean arterial pressure;Choking;Hoarseness and sore throat;Incidence of respiratory-related complications (atelectasis, hypoxemia, pulmonary infection).; | — |
Countries
China
Contacts
Public ContactSusu Zhou
Anhui Provincial Hospital
Outcome results
None listed