Hepatitis B-related acute-on-chronic liver failure
Conditions
Interventions
Wash intestinal bacteria treatment group:Wash intestinal bacteria transplantation
Conventional treatment group:Conventional treatment
Sponsors
First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1: Patients who are willing to sign informed consent; 2: Patients aged 18-60 years; 3: Diagnosing patients with HBV-related acute-on-chronic liver failure, classified as type A or type B, and staged as early or intermediate.
Exclusion criteria
Exclusion criteria: 1: Combined with HIV infection, hepatitis A, C, D, E virus infection, drug liver disease, alcoholic liver disease, etc.; 2: Type C liver failure, late liver failure; 3: Patients with severe heart failure, chronic obstructive pulmonary disease, cerebrovascular accident, gastrointestinal bleeding, etc. 4: Combined with primary peritonitis; 5: Bacterial or fungal infection of lung, urinary system and blood. 6: Combine patients with liver cancer, lung cancer, lymphoma, etc. malignant tumors; 7: Patients who have been taking anticoagulants for a long time, patients with mental and immune diseases; 8: Pregnant women or lactating women; 9: Patients who take antibiotics orally or intravenously; 10: Patients with CD4+ cells less than 200×10^6/mL.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 90-day survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of upper gastrointestinal bleeding, hepatic encephalopathy, and hepatorenal syndrome within 90 days; | — |
Countries
China
Contacts
Public ContactJinshui Pan
First Affiliated Hospital of Fujian Medical University
Outcome results
None listed