Obesity
Conditions
Interventions
Placebo group:Placebo
Sponsors
Inner Mongolia People's hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male or female, aged 18-65 years. 2. 28kg/m^2= Body mass index (BMI)=30kg/m^2; Male waist >90cm, female waist >85cm. 3. No antibiotics, anti-obesity drugs, probiotics or related preparations were used 1 month before enrollment. 4. No history of chronic gastrointestinal disease. 5. Agree to participate in the study and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant, breastfeeding or planning to become pregnant within the first six months. 2. Liver function complete: alanine aminotransferase and aspartate aminotransferase normal value of 2 times or more. 3. Renal insufficiency: glomerular filtration rate <90ml/min/1.72m^2. 4. Hypertension with blood pressure higher than 160/100 mmHg after treatment with 2 or more antihypertensive drugs. 5. Cardiac insufficiency; 6. Suffering from anemia or other blood diseases. 7. Diabetic patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition;Fecel metagenomics;Fecel metabolomics;Serum metabolomics;Inflammatory factor;Blood biochemistry;Intestinal mucosal barrier function; | — |
Countries
China
Contacts
Public ContactWang Huan
Inner Mongolia People's hospital
Outcome results
None listed