Knee osteoarthritis
Conditions
Interventions
Control group:The routine postoperative enhanced recovery protocol was performed without the use of low-intensity pulsed ultrasound
LIPUS group:In addition to the routine postoperative enhanced recovery protocol, low-intensity pulsed ultrasound with a frequency of 0.8MHz, a spatial peak temporal average acoustic intensity (SPTA) o
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients, aged 18-80 years old, with osteoarthritis who were undergoing primary unilateral TKA at our institution were consecutively enrolled.
Exclusion criteria
Exclusion criteria: 1. Robot-assisted TKA; 2. Diabetes mellitus with poor blood glucose control and associated with a high risk of infection; 3. Neuromuscular dysfunction affecting the lower extremities; 4. A severe coagulation disorder or thrombosis in the deep venous of the affected lower extremity; 5. Severe knee instability that could not be remedied with use of ligament retaining TKA; 6. Active systemic or local infectious lesions; 7. Knee flexion deformity or varus deformity of >30° ; 8. Opioid dependence, as defined by the usage of >100 mg of morphine milligram equivalents of opioids per week for pain management prior to surgery, for a duration of >3 months; 9. Body mass index of >40 kg/m^2; 10. Wear implantable electronic devices (e.g., pacemakers).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower-extremity swelling; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score;Range of motion of knee;Special Surgery Hospital score;Inflammatory biomarker;Biomarkers for muscle injury;Complication; | — |
Countries
China
Contacts
Public ContactJinwei Xie
West China Hospital of Sichuan University
Outcome results
None listed