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Study on 90% effective dose of ropivacaine for combined epidural anesthesia in patients with diabetic foot

Study on 90% effective dose of ropivacaine for combined epidural anesthesia in patients with diabetic foot

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088926
Enrollment
Unknown
Registered
2024-08-29
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic foot

Interventions

Experimental group:Bilateral sensory block at T12 level was achieved within 15 minutes after subarachnoid injection using an initial dose of 9mg ropivacaine, and success was recorded when surgery was

Sponsors

Hainan General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: In this study, patients diagnosed with diabetic foot debridement and drainage, toe amputation or foot amputation in Hainan Provincial People's Hospital were selected, and the patients agreed to the anesthesia method of lumbo-epidural anesthesia. All patients signed informed consent, regardless of gender or age, BMI<35kg/m2, and ASA grade I-III.

Exclusion criteria

Exclusion criteria: Patients with contraindications for intraspinal anesthesia such as spinal cord or radiculopathy, systemic severe infection or injection site infection, cotting dysfunction, allergy to amide local anesthetics, pre-existing sensory loss, inability to communicate with normal language, pregnant and lactating women, and participants in other clinical trials.

Design outcomes

Primary

MeasureTime frame
ED90 of ropivacaine based on successful or failed subarachnoid injection;

Secondary

MeasureTime frame
Intraoperative Complications;Usage of vasoactive drugs;

Countries

China

Contacts

Public ContactChen Wang

Hainan General Hospital

2396521095@qq.com+86 130 7062 6818

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026