Perioperative Neurocognitive Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The American Society of Anesthesiologists (ASA) grades I to III; (2) Age = 65 years old and = 95 years old, regardless of gender; (3) Hip fracture patients undergoing elective surgery under general anesthesia in the Department of Traumatology and Orthopedics at Yueyang Hospital: ? Femoral neck fracture, elective joint replacement or internal fixation surgery under general anesthesia; ? Femoral intertrochanteric fracture, scheduled for intramedullary nail fixation surgery under general anesthesia; (4) Understand and agree to participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Severe heart, liver, and kidney dysfunction; (2) Has a history of traumatic brain injury, mental illness, drug abuse, or alcoholism; (3) Equipped with a pacemaker or other electrical stimulation device; (4) ) Unable to effectively communicate and collaborate with doctors to complete cognitive function tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma inflammatory factors;Biological indicators; | — |
Countries
China
Contacts
Yueyang Hospital of integrated Traditional Chinese and WesternMedicine, Shanghai University of Traditional Chinese Medicine