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A Pan-Vascular Prospective Cohort-Based Study of the Effect of Lp (a) on Atherosclerosis in a Population with Diabetes Mellitus and Abnormal Blood Glucose

A Pan-Vascular Prospective Cohort-Based Study of the Effect of Lp (a) on Atherosclerosis in a Population with Diabetes Mellitus and Abnormal Blood Glucose

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088874
Enrollment
Unknown
Registered
2024-08-28
Start date
2024-02-15
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes

Interventions

diabetic, pre-diabetic and normal populations:no

Sponsors

The Third Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age 40-70 years old (including the threshold), gender is not limited; 2. ASCVD risk groups: (1) have a family history of early onset cardiovascular disease (male 10% or lifetime risk >32.8%); (9) Chronic Kidney Disease (CKD); those who satisfy any two of the above conditions, or those who have atherosclerosis such as arterial plaques, atherosclerosis or stenosis of blood vessels, etc., can be directly entered into the primary screening cohort. 3. Those who are able to voluntarily accept the monthly/yearly physical examination and follow up after the enrollment; 4. Those who agree to be enrolled in the study in a timely manner. ) Agree to feedback information related to diabetes diagnosis during outpatient visits to the investigator in a timely manner during the course of the study; 5. Those who are fully aware of the study and voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Persons with previous cardiovascular endpoint events: myocardial infarction, stroke, transient ischemic attack, coronary intervention or other revascularization procedures, unstable angina, and hospitalization due to acute heart failure events; 2. Persons who have undergone major surgical procedures such as transplantation and other surgical treatments; 3. Persons who suffer from autoimmune disorders, malignant neoplasms, hereditary disorders, and psychiatric disorders/disabilities that, in the judgment of the investigator, make it inadvisable to participation in this study; 4. those with poor compliance who, in the judgment of the investigator, are unable to complete the study.

Design outcomes

Primary

MeasureTime frame
Lp(a);Cervical Vascular Ultrasound;

Secondary

MeasureTime frame
height;weight;waist measurement;blood pressure;liver function;kidney function;fasting blood glucose;blood lipid;glycosylated haemoglobin;routine blood;homocysteine;Heart fatty acid protein;Myeloperoxidase;Electrocardiogram results;chest X-ray;Results of abdominal ultrasound;

Countries

China

Contacts

Public ContactJiangang Wang

Central South University Third Xiangya Hospital

600410@csu.edu.cn+86 156 0731 4653

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026