Gastric Precancerous Lesion
Conditions
Interventions
control group:Chinese herbal granules placebo, 1 sachet/dose, 1 time/day. Oral folic acid tablets 10mg/dose, 3 times/day.
Sponsors
Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Chronic atrophic gastritis was diagnosed by histopathology and conformed to the diagnostic criteria of traditional Chinese medicine; the age was = 18 years old and < 70 years old; all the HP positive patients had received anti-HP treatment and were enrolled in the HP negative group; those who had not received other treatment in the last month and did not participate in other new drug clinical trials; voluntarily signed informed consent form; passed the hospital ethics review.
Exclusion criteria
Exclusion criteria: Misdiagnosed as chronic atrophic gastritis; complicated with gastric ulcer, gastric hemorrhage, esophageal cancer and other digestive tract tumors; severe heart, brain, liver, kidney, lung and other diseases; major organ damage, dysfunction; complicated with hematological diseases, endocrine, tumors, autoimmune diseases; serious diseases need rescue, surgery and other treatment, can not continue this experiment; serious mental and nervous system diseases. People who are addicted to drugs such as aspirin and opiates; those who have bad habits such as alcoholism; those who need isolation treatment for severe infectious diseases; have contraindications or no history of drug allergy to useful drugs, are allergic to the drugs in this study; are pregnant or lactating; those who are positive for HP infection or are ineffective by anti-HP treatment; take proton pump inhibitors, H2 receptor antagonists, acid inhibitors, quinolones antibiotics or bismuth agents within one week. Experts from other research groups agree that it is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histopathological evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy of clinical symptoms;Criteria for judging the curative effect of TCM syndromes; | — |
Countries
China
Contacts
Public ContactXiongwen Wang; Huafeng Pan
Guangzhou University of Chinese Medicine/ Science and Technology Innovation Center,Guangzhou University of Chinese Medicine
Outcome results
None listed