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Clinical study of dexmedetomidine for analgesia in epidural delivery

Clinical study of dexmedetomidine for analgesia in epidural delivery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088860
Enrollment
Unknown
Registered
2024-08-28
Start date
2022-05-04
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

L-Dex group: 0.1ug/ml dexmedetomidine+0.08% ropivacaine:Epidural application
H-Dex group: 0.2ug/ml dexmedetomidine+0.08% ropivacaine:Epidural application
SF group: 0.25ug/ml sufentanil+0.08% ropivacaine:Epidural application

Sponsors

Shanghai 10th People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Full term primiparous expectant mothers; 2. Age 20-35 years old; 3. Fetal absence of complications such as intrauterine distress, amniotic fluid contamination, cephalopelvic imbalance, and intrauterine infection; 4. All sign informed consent forms; 5. Willing to follow research requirements

Exclusion criteria

Exclusion criteria: 1. Pregnant women with concomitant mental illness, cardiovascular and other important organ diseases; 2. Pregnant women without postoperative pain relief requirements; 3. There are contraindications for spinal anesthesia; 4. Opioid drug addicts; 5. Pregnant women with abnormal fetal heart rate monitoring (fetal heart rate>160 beats/minute or<120 beats/minute, lasting for 10 minutes)

Design outcomes

Primary

MeasureTime frame
Pain score;

Secondary

MeasureTime frame
body temperature;epidural anesthesia block level;Improved Bromage rating;blood pressure;heart rate;Rate of vaginal delivery to cesarean section;Duration of the first stage of labor;Second stage of labor duration;Duration of the third stage of labor;The analgesic duration;Neonatal Apgar score;Perceived blockade score;Adverse reactions;

Countries

China

Contacts

Public ContactNiu Xiaoyin

Shanghai 10th People's Hospital

nxy19880705@163.com+86 137 6183 5270

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026