lumbar disc herniation
Conditions
Interventions
Combined treatment group:Percutaneous Endoscopic Interlaminar Discectomy, Epidural administration of dexamethasone in combination with VB12
Single surgery group:Percutaneous Endoscopic Interlaminar Discectomy
Sponsors
The 908th Hospital of Chinese People’s Liberation Army Joint Logistic Support Force
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) diagnosis of lumbar intervertebral disc herniation, ineffective after strict conservative treatment for more than 3 months; (2) patients' symptoms, signs and imaging manifestations were compatible, and the responsible interspace was L4/5 or L5/S1 level; (3) there were no obvious contraindications to surgery in the preoperative examination.
Exclusion criteria
Exclusion criteria: (1) multiple segmental lesions all requiring surgery or recurrence after surgical treatment; (2) combined cardiopulmonary, hepatic, and renal functions with severe impairment; (3) complicated intervertebral space infections or postoperative wound infections; (4) hypersensitivity to dexamethasone and vitamin B12, or contraindications to their use; (5) incomplete clinical data, inability to cooperate with the follow-up visit, and refusal to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Visual Analog Scale scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| 0swestry disability index;Japanese Orthopaedic Association Scores;Modified MacNab efficacy evaluation criteria;PGE2;TNF-a;IL-6; | — |
Countries
China
Contacts
Public ContactHe Cheng
The 908th Hospital of Chinese People’s Liberation Army Joint Logistic Support Force
Outcome results
None listed