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Continuous high power short duration ablation for pulmonary vein isolation based on ablation index: Safety, efficacy and long-term durability

Safety and efficacy of continuous high power short duration radiofrequency ablation guided by ablation index in atrial fibrillation ablation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088816
Enrollment
Unknown
Registered
2024-08-27
Start date
2024-08-28
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

Continuous high power ablation group:Continuous high power ablation
Interrupted high power ablation group:Interrupted high power ablation
Interrupted low power ablation group:Interrupted low power ablation

Sponsors

The Second Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients with symptomatic atrial fibrillation diagnosed by conventional 12-lead ECG or 24-hour Holter ECG, with poor symptom control or intolerance after treatment with at least one anti-arrhythmic drug, including paroxysmal atrial fibrillation and persistent atrial fibrillation 2. Patients with symptomatic atrial fibrillation prefer to radiofrequency ablation after fully weighing the benefits and risks before using antiarrhythmic drugs

Exclusion criteria

Exclusion criteria: 1.age 80 years old, 2.left atrium (LA) diameter > 50 mm, 3.the presence of a mechanical mitral valve prosthesis 4.impaired thyroid function 5.left ventricular ejection fraction < 40% 6.contraindication for anticoagulant therapy 7.current malignancy 8.prior catheter or surgical AF ablation 9.life expectancy < 1 year

Design outcomes

Secondary

MeasureTime frame
Procedure time;First-pass isolation rate of LPV and RPV;First-pass isolation time of LPV/RPV ;Bilateral pulmonary vein isolation time;

Primary

MeasureTime frame
Post-operative heart rhythm status;

Countries

China

Contacts

Public ContactHongtao Wang

The Second Affiliated Hospital of Xi'an Jiaotong University

wht1977506@163.com+86 138 9194 4803

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026