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Assessment and Mechanistic Investigation of Cognitive Impairment Following Hemorrhagic Stroke

Assessment and Mechanistic Investigation of Cognitive Impairment Following Hemorrhagic Stroke

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088795
Enrollment
Unknown
Registered
2024-08-27
Start date
2024-08-30
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhagic Stroke, Subarachnoid Hemorrhage

Interventions

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: According to the "Chinese Guidelines for the Diagnosis and Treatment of Aneurysmal Subarachnoid Hemorrhage," published by the Stroke Prevention and Control Engineering Committee of the National Health and Family Planning Commission in 2016, a head CT scan indicating subarachnoid hemorrhage, along with confirmation of an intracranial aneurysm using CT angiography (CTA), digital subtraction angiography (DSA), or magnetic resonance angiography (MRA), is required.The diagnosis of spontaneous intracerebral hemorrhage is based on the "Chinese Guidelines for the Clinical Management of Cerebrovascular Diseases 2023" and the "American Heart Association/American Stroke Association Guidelines for the Management of Spontaneous Intracerebral Hemorrhage 2022." It requires CT confirmation of a hemorrhagic lesion in the brain parenchyma, while ruling out secondary causes such as trauma and vascular diseases, as described below.

Exclusion criteria

Exclusion criteria: 1) Exclude traumatic subarachnoid hemorrhage, hematologic diseases, coagulation disorders, hypertensive cerebral hemorrhage with intraventricular extension, arteriovenous malformations (AVM) and other intracranial vascular malformations, moyamoya disease, intracranial tumor stroke, pseudoaneurysms, etc. 2) Exclude congenital hydrocephalus and hydrocephalus that existed prior to subarachnoid hemorrhage. 3) Exclude pregnant patients. 4) Exclude patients with age less than 18 years

Design outcomes

Primary

MeasureTime frame
mRS score at 6 months;

Secondary

MeasureTime frame
In-hospital mortality;mRS score at 3 months;MoCA score at 3 months;MoCA score at 6 months;

Countries

China

Contacts

Public ContactLu Ma

West China Hospital, Sichuan University

alex80350305@outlook.com+86 186 1322 8772

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026