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Analysis of efficacy and safety of Ab Externo XEN gel stent implantation in the treatment of glaucoma

Analysis of efficacy and safety of Ab Externo XEN gel stent implantation in the treatment of glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088780
Enrollment
Unknown
Registered
2024-08-27
Start date
2024-08-31
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Case series (glaucoma):None

Sponsors

Hangzhou Branch of Eye and Optometry Hospital, Affiliated with Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1)Patients diagnosed with primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG), or secondary glaucoma (SG) at the Hangzhou Branch of Eye and Optometry Hospital, Affiliated with Wenzhou Medical University;(2)Patients voluntarily opting for ab externo XEN gel stent implantation surgery, and having no prior history of XEN gel stent implantation;(3)Patients undergoing regular follow-up visits postoperatively, with the last follow-up occurring at least 1 year after the surgery.

Exclusion criteria

Exclusion criteria: (1)Patients with active ocular diseases (such as keratitis, retinal disorders, etc.) within one month before surgery;(2)Preoperative assessment indicating anterior chamber depth <2mm;(3)History of allergy to glutaraldehyde or porcine derivatives;(4)Patients who are pregnant or breastfeeding;(5) Patients with severe physical or mental health issues, such as end-stage heart disease, kidney disease, pulmonary disease, or advanced tumors;(6) Non-compliance with signing the informed consent form for the study.

Design outcomes

Primary

MeasureTime frame
Intraocular pressure;Number of IOP-lowering drugs;Surgical success rate;Surgical-related complications;

Secondary

MeasureTime frame
Vision;Anterior chamber depth;Filtering bleb morphology;XEN gel stent status;

Countries

China

Contacts

Public ContactJunhua Li

Hangzhou Branch of Eye and Optometry Hospital, Affiliated with Wenzhou Medical University

dr.ljh@eye.ac.cn+86 152 6715 7997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026