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A Study on the Morphology of the Ciliary Body in Patients with Primary Angle-Closure and Primary Angle-Closure Glaucoma.

A Study on the Morphology of the Ciliary Body in Patients with Primary Angle-Closure and Primary Angle-Closure Glaucoma.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088753
Enrollment
Unknown
Registered
2024-08-26
Start date
2022-12-10
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

Primary angle closure:No intervention

Sponsors

National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
49 Years to 83 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing phacoemulsification cataract extraction and intraocular lens implantation combined with goniosynechialysis guided by gonioscopy; (2) Patients diagnosed with primary angle-closure (PAC); (3) Patients diagnosed with cataracts.

Exclusion criteria

Exclusion criteria: (1) Patients with a history of ocular surgery (except for laser peripheral iridotomy), trauma, iris or angle neovascularization, pseudoexfoliation, or iris or corneal abnormalities, as well as those with any form of secondary angle-closure glaucoma; (2) Any other ocular diseases (except for refractive errors); (3) Poor cooperation during preoperative examinations, leading to unreliable results or missing data (e.g., inability to tolerate gonioscopy or ultrasound biomicroscopy); (4) Continuous use of medications such as pilocarpine or prostaglandins that may affect the ciliary body morphology; (5) Eyes with more than two quadrants of peripheral anterior synechiae (PAS) and poor intraocular pressure control after medication treatment.

Design outcomes

Primary

MeasureTime frame
Trabecular ciliary process angle;Iris ciliary process angle;Trabecular ciliary process distance;Iris ciliary process distance;Ciliary body thickness at point of the scleral spur;Ciliary body thickness 1000µm from the scleral spur;

Secondary

MeasureTime frame
Anterior chamber depth;Angle opening distance at 500µm from the scleral spur;Trabecular iris space area at 500µm from the scleral spur;

Countries

China

Contacts

Public ContactLi Junhua

National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China

54064308@qq.com+86 152 6715 7997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026