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Effect of ultrasound-guided nerve block on inflammatory response in enhanced recovery after thoracoscopic surgery

Effect of ultrasound-guided nerve block on inflammatory response in enhanced recovery after thoracoscopic surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088735
Enrollment
Unknown
Registered
2024-08-26
Start date
2024-05-15
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary tumors

Interventions

TPVB combined general anesthesia group:General anesthesia was performed after thoracic paravertebral nerve block
SAPB combined general anesthesia group:General anesthesia was performed after serratus anterior plane block
general anesthesia group:general anesthesia only

Sponsors

Beijing Aerospace General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: a) Patients undergoing selective pulmonary segmentectomy or lobectomy; b)ASA I~II level; c) Age 18-65 years old; d) Informed consent signed by patients or family members.

Exclusion criteria

Exclusion criteria: a) Hypersensitivity to local anesthetics; b) Combined with autoimmune diseases, long-term use of steroids, non-steroidal anti-inflammatory drugs analgesics; c) Combined with sleep disorders, long-term use of hypnotic drugs; d) Infection in the blocked area or coagulation dysfunction; e) Severe obesity, BMI=30.

Design outcomes

Primary

MeasureTime frame
7 Cytokines (IL-2,IL-4,IL-6,IL-10,IL-17A,TNF-a,IFN-?);C-reactive protein;

Secondary

MeasureTime frame
Invasive blood pressure(Before induction, after intubation ,when cutting skin);postoperative pain(12,24 and 48 hours after surgery);Sleep quality the first night after surgery;

Countries

China

Contacts

Public ContactTian Xiong

Beijing Aerospace General Hospital

22346399@qq.com+86 138 1117 5393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026